Jignesh Parmar

Postdoctoral Fellow Center for Quantitative Medicine, Dr. Pedro Mendes's Group, UCONN Health, Univ. Conneticut, 263 Farmington Ave., Farmington, CT 06030 Email: jignesh.h@gmail.com Tel: 860-679-7516

Link to Jignesh at UCONN Health
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Previous position at VT: Postdoctoral Fellow, 2011-15.

Research Pages: Tyson Lab

Current Research Interests

I am currently working with Prof. John Tyson, Dept. of Biological Science and with Prof. William Baumann, Dept. of Electrical and Computer Engineering at Virginia Tech. My research work involves developing mathematical models for signaling pathways in estrogen receptor-positive breast cancer cells. The models are used to explore various regulatory mechanisms that may lead to resistance to antiestrogen drugs.

Education

Ph.D. 2010 Indian Institute of Technology at Bombay, India, Chemical Engineering
M.S. 2004 Indian Institute of Science at Bangalore, India, Chemical Engineering.
B.S. 2000 Gujarat University, India, Chemical Engineering.

Professional Experience

2011 - Postdoctoral Fellow

Publications

Tavassoly, I., Parmar, J.H., Shajahan-Haq, A.N., Clarke, R., Baumann, W.T., and Tyson, J.J. (2015). Dynamic modeling of the interaction between autophagy and apoptosis in mammalian cells. CPT Pharmacometrics Syst. Pharmacol. 4 (4): 263-272.
[Abstract] [Article]
Parmar, J.H., Cook, K.L., Shajahan, A.N., Clarke, P., Tavassoly, I., Clarke, R., Tyson, J.J., and Baumann, W.T. (2013). Modeling the effect of GRP78 on anti-estrogen sensitivity and resistance in breast cancer. Interface Focus 3:20130012.
[Abstract] [Article]
Parmar, J. H., Venkatesh, K. V., and Bhartiya, S. (2012). Quantification of metabolism in Saccharomyces cerevisiae under hyperosmotic conditions using elementary mode analysis. J. Ind. Microbiol. Biotechnol. 39:927-941.
[Abstract] [Article]
Parmar, J. H., Bhartiya, S., and Venkatesh, K. V. (2011). Characteriazation of the adaptive response and growth upton hyperosmotic shock in Saccharomyces cerevisiae. Mol. Biosyst. 7:1138-1148.
[Abstract] [Article]
Parmar, J. H., Bhartiya, S., and Venkatesh, K. V. (2009). A model-based study delineating the roles of the two signaling branches of Saccharomyces cerevisiae, Sho1 and Sln1, during adaptation to osmotic stress. Phys. Biol. 6:036019.
[Abstract] [Article]

Conference Proceedings

Parmar J. H., Venkatesh, K.V., and Bhariya, S. (2009). Dynamic modeling of osmotic stress response of yeast. National Symposium on Theoretical and Mathematical Biology. Oct 10-11. Pune, India.
Parmar J. H., Venkatesh, K.V., and Bhariya, S. (2009). Phenotype analysis of osmoadaptation process in Saccharomyces cerevisiae. The 10th International Conference on System Biology (ICSB 2009) Aug. 30 - Sep.4., Stanford, CA.
Parmar J. H., Venkatesh, K.V., and Bhariya, S. (2009). Characterization of the adaptive response upon hyperosmotic shock in Saccharomyces cerevisiae. The International Conference on Foundations of Systems Biology in Engineering (FOSBE 2009) Aug. 9-12. Denver, CO.
Parmar J. H., Venkatesh, K.V., and Bhariya, S. (2008). Delineating the relative roles of two independent signaling branches of the HOG pathway: a simulation study. The 9th International Conference on System Biology (ICSB 2008) Aug. 22-28, Gothenburg, Sweden.

Personal

I was born in Visnagar, a small town in state of Gujarat, India. By grace of GOD and my Parents, I have got this opportunity to work in this lab. I reside with my wife Hetal and my sweat little daughter Shreya in Blacksburg, Virginia. When I am not working, I spend time in playing with my daughter, listening to music and doing Yoga.