Pavel Kraikivski

Research Scientist Department of Biological Sciences Virginia Tech Blacksburg, VA 24061-0406 Email: pavelkr@vt.edu Tel: 540-231-6398 Fax: 540-231-9307

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Research Pages: Tyson Lab

Current Research Interests

Education

Ph.D. 2005 Max-Planck Institute for Colloids and Interfaces, Potsdam University, Germany, Biophysics.
M.S. 2002 Ioffe Physical-Technical Institute, Saint Petersburg State Polytechnical University, Russia, Physics.
B.S. 2000 Saint Petersburg State Polytechnical University, Russia, Physics.

Professional Experience

2011 - Present Research Faculty, Department of Biological Sciences, Virginia Tech. Cell cycle control, (Prof. John Tyson lab).
2006 - 2011 Postdoctoral Fellow, Center for Cell Analysis and Modeling, Department of Cell Biology, University of Connecticut Health Center. Biological pathway quantification, intracellular transport, kinetics of actin dendritic nucleation, cell motility, Cytoskeletal Filaments, actin bundling, diffusion in crowded cytoplasm, and contribution to VCell development. (Prof. L.M. Loew laboratory, Prof. B.M. Slepchenko, and Prof. V. Rodionov).
2002 - 2006 Ph.D. Candidate. Max-Planck Institute for Colloids and Interfaces, Germany. Semiflexible polymers adsorbed on structured substrates. Collective ilament dynamics in motility assays for motor proteins. Short- and long- working distance optical trappings. (Prof. R. Lipowsky, Prof. Jan Kierfeld and Dr. R. Dimova).
1999 - 2002 Research Technician. Institute for Analytical Instrumentation Russian Academy of Science, Russia. Electrospray ionization mass spectrometry, optical emission spectroscopy. (Prof. L.N. Gall laboratory).
1997 - 2002 Research Technician. Ioffe Physical-Technical Institute of the Russian Academy of Sciences, and St.-Petersburg State Technical University, Russia. Glassy chalcogenide semiconductors, electron paramagnetic resonance spectroscopy. (Prof. K. D. Tsendin and Prof. K.F. Shtel’makh laboratories).
For a detailed description of Pavel' research interest and professional experience, please visit his research website.

Publications

Kraikivski, P., Chen, K.C., Laomettachit, T., Murali, T.M., and Tyson, J.J. (2015). From START to FINISH: computational analysis of cell cycle control in budding yeast. NPJ Syst. Biol. Appl. 1: 15016.
[Abstract] [Article]
Lomakin, A. J., Kraikivski, P., Semenova, I., Ikeda, K., Zaliapin I., Tirnauer, J. S. Akhmanova, A., and Rodionov, V. (2011). Stimulation of the CLIP-170-dependent capture of membrane organelles by microtubules through fine-tuning of microtubule assembly dynamics. Mol. Biol. Cell. 22:4029-4037.
[Abstract] [Article]
Novak, I. L., Gao, F., Kraikivski, P., and Slepchenko, B. M. (2011). Diffusion amid random overlapping obstacles: Similarities, invariants, approximations. J. Chem. Phys. 134:154104.
[Abstract]
Kraikivski, P., and Slepchenko, B. M. (2010). Quantifying a pathway: kinetic analysis of actin dendritic nucleation. Biophys. J. 99:708-715.
[Abstract] [Article]
Lomakin, A. J., Semenova, I., Zaliapin, I., Kraikivski, P., Nadezhdina, E., Slepchenko, B. M., Akhmanova, A., and Rodionov, V. (2009). CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport. Dev. Cell 17:323–333.
[Abstract] [Article]
Novak, I. L., Kraikivski, P., and Slepchenko. B. M. (2009). Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures. Biophys. J. 97:758-767.
[Abstract] [Article]
Kierfeld, J., Frentzel, K., Kraikivski, P., and Lipowsky, R. (2008). Active dynamics of filaments in motility assays. Eur. Phys. J. Special Topics 157:123-133.
[Abstract]
Kraikivski, P., Slepchenko, B. M., and Novak, I. L. (2008). Actin bundling: initiation mechanisms and kinetics. Phys. Rev. Lett. 101:128102.
[Abstract] [Article]
Kierfeld, J., Kraikivski,P., Kühne, T., and Lipowsky, R. (2007). Cooperative behaviour of semiflexible polymers and filaments. In Traffic and Granular Flow `05, (A. Schadschneider, T. Pöschel, R. Kühne, M. Schreckenberg, and D.E. Wolf Eds), pp 239-249 (Springer, Berlin).
[Abstract]
Kierfeld, J., Kraikivski,P., and Lipowsky, R. (2006). Filament ordering and clustering by molecular motors in motility assays. Biophys. Rev. Lett. 1:363-374.
[Abstract]
Kierfeld, J., Gutjahr, P., Kühne, T., Kraikivski, P., and Lipowsky, R. (2006). Buckling, bundling, and pattern formation: from semi-flexible polymers to assemblies of interacting filaments. J. Comput. Theor. Nanosci. 3:898-911.
[Abstract]
Kraikivski, P., Lipowsky, R. and Kierfeld, J. (2006). Enhanced ordering of interacting filaments by molecular motors. Phys. Rev. Lett. 96:258103.
[Abstract]
Kraikivski, P., Pouligny, B., and Dimova, R. (2006). Implementing both short- and long-working-distance optical trappings into a commercial microscope. Rev. Sci. Instrum. 77:113703.
[Abstract] [Article]
Kraikivski, P., Lipowsky, R., and Kierfeld, J. (2005). Point force manipulation and activated dynamics of polymers adsorbed on structured substrates. Europhys. Lett. 71:138-144.
[Abstract] [Article]
Kraikivski, P., Lipowsky, R., and Kierfeld, J. (2005). Activated dynamics of semiflexible polymers on structured substrates. Eur. Phys. J. E. Soft Matter 16:319-340.
[Abstract] [Article]
Kraikivski, P., Lipowsky, R., and Kierfeld, J. (2004). Barrier crossing of semiflexible polymers. Europhys. Lett. 66:763-769.
[Abstract] [Article]
Kraikivski, P., and Gall, L.N. (2004). Optical tweezers: applications in biophysics. Nauch. Priborostroenie (Scientific Instrumentation) 14: 10-17.
Kraikivski, P., and Gall, L.N. (2004). Measuring forces and velocities of motor proteins by a trapped microtubule. Nauch. Priborostroenie (Scientific Instrumentation) 14: 48-56.

Personal

Pavel is from St. Petersburg, the most beautiful city in Russia. When not working, Pavel likes to spend time playing with his son. He is also keen on traveling, hiking and mountain skiing.