Tongli Zhang
Assistant Professor Dept. Molecular & Cellular Physiology College of Medicine, Univ. Cincinnati Cincinnati, OH 45267-0576 Email: tongli.zhang@uc.edu Tel: 513-558-6156Link to Tongli at U. Cincinnati
Research Pages: Tyson Lab Budding Yeast Cell Cycle Model Generic Cell Cycle Model
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Previous position at VT: PhD student, 2004-08; Postdoc, 2009.
Current Research Interests
Living organisms have to respond properly to internal and external signals for their survival. The information processing and decision making of the cells are carried out by their molecular machineries. Mutations of the machinery often disturb the cell physiology and cause ill effects, such as the development of tumor. My aim is to understand the signal transduction pathways in mammalian cells.
We collect biochemical and physiological information from the literature and from our experimental collaborators, and then unite them into a consistent picture with the help of mathematical modeling and computer simulation. We use the model to generate novel predictions, which can be tested by our collaborators, to further refine our model.
With a realistic mathematical model, we will propose practical protocols to intervene and to fix faulty cellular responses. The protocols will hopefully contribute to tumor treatment.
Education
| Ph.D. | 2008 | Virginia Tech, Genomics, Bioinformatics and Computational Biology. |
| M.S. | 2003 | China Medical University, Shenyang, China, Biochemistry and Molecular Biology. |
| B.S. | 2000 | China Medical University, Shenyang, China, Forensic Medicine. |
Professional Experience
| Jan 2009 - Oct 2009 | Postdoctoral Fellow, Dr. John Tyson's Lab, Virginia Tech, Blacksburg, VA |
| Sep 2004 - Dec 2008 | PhD Student, Genetics Bioinformatics and Computational Biology Program, Virginia Tech |
| Aug 2003 - Jun 2004 | Instructor, Department of Bioengineering, YanShan University, Qinhuangdao, China |