Cdc6, as well as Sic1, is a potent inhibitor of Clb2. Therefore over-expression of either one will rescue the telophase arrest of CLB2-db∆.
Genotype | Phenotype |
CLB2-db∆ CLB2-db∆ GAL-SIC1 CLB2-db∆ GAL-CDC6 |
Arrests in telophase (Wasch & Cross, 2002). Viable (Cross, 2003). Viable (prediction). |