- APC Mutants
- APC-A
- APC-A cdh1∆
- APC-A cdh1∆ in galactose
- APC-A cdh1∆ GAL-SIC1
- APC-A cdh1∆ GAL-CDC6
- APC-A cdh1∆ multi-copy SIC1
- APC-A cdh1∆ multicopy CDC6
- APC-A cdh1∆ multicopy CDC20
- APC-A sic1∆
- APC-A sic1∆ cdc6∆2-49
- APC-A GAL-CLB2
- cln1∆ cln2∆ cln3∆ apc-ts
APC-A
debug: ,
test user =
test db =
Simulation:
Change of parameters: ka20"=0.
Length of G1 phase: 27.4 min.
Mass at division: 3.86.
Experiments:
Rudner, A.D. and Murray, A.W. (2000b). Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex. J. Cell Biol. 149:1377-1390.
[Abstract] [Article]
[Abstract] [Article]
Cross, F.R. (2003). Two redundant oscillatory mechanisms in the yeast cell cycle. Dev. Cell 4:741-752.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Rudner: Fig. 6, viable. Sister separation is delayed by 20 min, Clb2 degradation is delayed by more than 40 min.
Comments: In simulation, G2 is longer than WT by 9 min.