Modeling the Budding Yeast Cell Cycle

clb5∆ clb6∆

Simulation:

Change of parameters: ksb5'=ksb5"=0.
Length of G1 phase: 73.4 min.
Mass at division: 3.13.

Experiments:

Schwob, E. and Nasmyth, K.(1993). CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 7:1160-1175.
[Abstract] [Article]
Experimental results: Fig. 4, onset of S phase is delayed relative to budding by about 30 minutes.
Comments: In simulation, onset of S phase is delayed by 45 min after bud initiation.