Modeling the Budding Yeast Cell Cycle

• Home
• Introduction
• Rationale
• Budding yeast biology
• Components & function
• Cell cycle progression
• Basic mechanism
• Major improvement
• Overview
• Wiring diagram
• Description
• Justification
• Cyclins
• Cdc20
• Cdh1
• Cdc14 activation
• Mitotic Exit Network
• Pds1/Esp1 interaction
• CKI
• Checkpoint proteins
• Formulation
• Simulation
• Conclusions
• Mathematical Model
• Equations
• Parameters
• Problems
• Predictions
• Robustness
• Mutants
• List of Mutants
• WT in glucose
• WT in galactose
• Cln
• Bck2
• cln1 cln2 cln3
• Clb5 Clb6
• Clb1 Clb2
• Sic1
• Cdc6
• Cdh1
• Cdc20
• APC
• MEN pathway
• Exit-of-mitosis
• Pds1 / Esp1
• Checkpoint
• PPX
• Model Downloads
• Previous model
• Current model
• Target model
• APC-del model
• Modeling Tools
• Get WinPP
• How to use WinPP
• JigCell
• Oscill8
• PET
• Simulate the Model
• Other Models
• The "target" model
• "APC-del" model
• Generic model
• Literature
• References
• Publications
• Who We Are
• Va Tech
• BUTE
• Rockefeller Univ.

• Clb5%20Clb6 Mutants

Simulation:

Experiments: