Modeling the Budding Yeast Cell Cycle

cln1∆ cln2∆ cln3∆ GAL-CLN2

Simulation:

Change of parameters: ksn2'=0.12, ksn2"=0, Dn3=0, MDT=150.
Length of G1 phase: 68.4 min.
Mass at division: 1.55.

Experiments:

Cross, F.R. and Tinkelenberg, A.H. (1991). A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle. Cell 65:875-883.
[Abstract] [Article]
Experimental results: Fig. 4, viable.
Comments: