Modeling the Budding Yeast Cell Cycle

swi5∆ GAL-CLB2

Simulation:

Change of parameters: ksswi'=ksswi"=0, ksb2=0.12, MDT=150.
Arrest: Telophase arrest.

Experiments:

Toyn, J.H., Johnson, A.L., Donovan, J.D., Toone, W.M., Johnston, L.H. (1997). The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase. Genetics 145:85-96.
[Abstract] [Article]
Experimental results: Inviable.
Comments: