Modeling the Budding Yeast Cell Cycle

swi5∆

Simulation:

Change of parameters: kswi'=kswi"=0.
Length of G1 phase: 23.3 min.
Mass at division: 2.37.

Experiments:

Toyn, J.H., Johnson, A.L., Donovan, J.D., Toone, W.M., Johnston, L.H. (1997). The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase. Genetics 145:85-96.
[Abstract] [Article]
Giaever, G., Chu, A.M., Ni, L., Connelly, C., Riles, L., Veronneau, S. et al. (2002). Functional profiling of the Saccharomyces cerevisiae genome. Nature 418:387-391.
[Abstract] [Article]
Experimental results: Viable.
Comments: