Generic Cell Cycle Model

wild-type S. cerevisiae

Simulation:

Change of parameters:

Experiments:

Brewer, B.J., Chlebowicz-Sledziewska, E. and Fangman, W.L. (1984). Cell cycle phases in the unequal mother/daughter cell cycles of Saccharomyces cerevisiae. Mol. Cell. Biol. 4:2529-2531.
[Abstract] [Article]
Chen, K.C., Calzone, L., Csikasz-Nagy, A., Cross, F.R., Novak, B. and Tyson, J.J. (2004). Integrative analysis of cell cycle control in budding yeast. Mol. Biol. Cell 15:3841-3862.
[Abstract] [Article]
Experimental results:
Comments: Parameters are set up to fit simulations of Chen et al., 2004. MDT - Mass doubling time