- Cdc20 Mutants
- cdc20-ts
- cdc20∆ clb5∆
- cdc20∆ pds1∆
- cdc20∆ pds1∆ clb5∆
- CLB5-db∆ pds1∆ cdc20∆
- cdc20-ts bub2∆
- cdc20-ts mad2∆
- net1∆ cdc20-ts
- GAL-ESP1 cdc20-ts
- GAL-CDC20
- APC-A cdh1∆ multicopy CDC20
- sic1∆ cdh1∆ GALL-CDC20
- sic1∆ cdc6∆2-49 cdh1∆ GALL-CDC20
GAL-ESP1 cdc20-ts
debug: ,
test user =
test db =
Simulation:
Change of parameters: ks20'=ks20"=0, ESP1T=20 (=20X WT), MDT=150.
Arrest: Telophase arrest.
Experiments:
Ciosk, R., Zachariae, W., Michaelis, C., Shevchenko, A., Mann, M. and Nasmyth, K. (1998). An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93:1067-1076.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Sister chromatids separate, Clb2 may not be degraded.
Comments:
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