- Cdc20 Mutants
- cdc20-ts
- cdc20∆ clb5∆
- cdc20∆ pds1∆
- cdc20∆ pds1∆ clb5∆
- CLB5-db∆ pds1∆ cdc20∆
- cdc20-ts bub2∆
- cdc20-ts mad2∆
- net1∆ cdc20-ts
- GAL-ESP1 cdc20-ts
- GAL-CDC20
- APC-A cdh1∆ multicopy CDC20
- sic1∆ cdh1∆ GALL-CDC20
- sic1∆ cdc6∆2-49 cdh1∆ GALL-CDC20
cdc20∆ clb5∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ks20'=ks20"=0, ksb5'=ksb5"=0.
Length of G1 phase: 57.4 min.
Arrest: Metaphase arrest.
Experiments:
Shirayama, M., Toth, A., Galova, M. and Nasmyth, K. (1999). APC(CDC20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature 402:203-207.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 2, metaphase arrest.
Comments:
webmaster