Modeling the Budding Yeast Cell Cycle

• Home
• Introduction
• Rationale
• Budding yeast biology
• Components & function
• Cell cycle progression
• Basic mechanism
• Major improvement
• Overview
• Wiring diagram
• Description
• Justification
• Cyclins
• Cdc20
• Cdh1
• Cdc14 activation
• Mitotic Exit Network
• Pds1/Esp1 interaction
• CKI
• Checkpoint proteins
• Formulation
• Simulation
• Conclusions
• Mathematical Model
• Equations
• Parameters
• Problems
• Predictions
• Robustness
• Mutants
• List of Mutants
• WT in glucose
• WT in galactose
• Cln
• Bck2
• cln1 cln2 cln3
• Clb5 Clb6
• Clb1 Clb2
• Sic1
• Cdc6
• Cdh1
• Cdc20
• APC
• MEN pathway
• Exit-of-mitosis
• Pds1 / Esp1
• Checkpoint
• PPX
• Model Downloads
• Previous model
• Current model
• Target model
• APC-del model
• Modeling Tools
• Get WinPP
• How to use WinPP
• JigCell
• Oscill8
• PET
• Simulate the Model
• Other Models
• The "target" model
• "APC-del" model
• Generic model
• Literature
• References
• Publications
• Who We Are
• Va Tech
• BUTE
• Rockefeller Univ.

Download current model (no_target)

Chen, K.C., Calzone, L., Csikasz-Nagy, A., Cross, F.R., Novak, B. and Tyson, J.J. (2004). Integrative analysis of cell cycle control in budding yeast. Mol. Biol. Cell 15:3841-3862.
[Reference Link]

To download, right click and choose "Save Target As" for Internet Explorer, or "Save Link Target As" for Netscape.

 

	ode	set
Winpp format	bychen04.ode	bychen04.set
Xpp format	bychen04_xpp.ode	bychen04_xpp.set
SBML format	yeast_rev20.sbml
MATLAB format	main_yeast.m GK.m event_yeast.m eqns.m	variable_name.m initial_conds.m

Many thanks to Kartik Subramanian (Virginia Tech) and Kamaludin Dingle (Oxford University, UK) to convert the current model files to MATLAB format and made them avaialable to download in Sept. 2010.