Modeling the Budding Yeast Cell Cycle

Predictions (iv):

The viability of CLB5-db∆ depends on Sic1 inhibition of Clb5 activity, but not on Cdc6.



Genotype Phenotype

CLB5-db∆ sic1∆

 

CLB5-db∆ cdc6∆2-49


Inviable, inefficient origin licensing (Wasch & Cross, 2002).

Viable, size similar to WT (prediction).



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