Modeling the Budding Yeast Cell Cycle

Parameters

Basal parameter values for the wild-type (WT) cell cycle. All parameters that start with a lower case k are rate constants (min-1) and all other parameters are dimensionless.

Click on the parameter to see its definition and its allowable range for a viable cell cycle. A description of how the parameters are related to experimental measurements is presented in Chen et al., 2004 .


           

   
           

           

Initial Conditions for a newborn WT daughter cell:


[mass]

1.2060

 

[F5]

7.2e-5

 

[Cdc14]

0.4683

[Cln2]

0.0652

 

[F2P]

0.0274

 

[Net1]T

2.8

[Clb5]

0.0518

 

[F5P]

7.9e-6

 

[Net1]

0.0186

[Clb2]

0.1469

 

[Swi5]T

0.9765

 

[RENT]

1.0495

[Sic1]

0.0229

 

[Swi5]

0.9562

 

[PPX]

0.1232

[Sic1P]

0.0064

 

[IEP]

0.1015

 

[Pds1]

0.0256

[C2]

0.2384

 

[Cdc20]T

1.9163

 

[Esp1]

0.3013

[C5]

0.0701

 

[Cdc20]A

0.4443

 

[ORI]

0.0009

[C2P]

0.0240

 

[Cdh1]T

1

 

[BUD]

0.0085

[C5P]

0.0069

 

[Cdh1]

0.9305

 

[SPN]

0.0305

[Cdc6]

0.1076

 

[Tem1]

0.9039

 

0.01

[Cdc6P]

0.0155

 

[Cdc15]

0.6565

 

0.2

[F2]

0.2361

 

[Cdc14]T

2

 

0.1