Modeling the Budding Yeast Cell Cycle

Budding Yeast Model

Mathematical formulation:

We formulate the complex regulatory network as a set of nonlinear differential equations according to the wiring diagram. Using a basal parameter set, attributable to wild-type division cycles, we solve the equations numerically with a computer program WinPP.

A description of how the equations are formulated, and how the parameters are related to experimental measurements is presented in the Materials and Methods in Chen et al., 2004. A verbal description of the name for each parameter and its allowable range (that will give a viable cell cycle) can be found here.