Modeling the Budding Yeast Cell Cycle

Predictions (ix):

When Cdc20 is crippled, like in APC-A mutants, Cdh1 is more important than the CKIs in getting out of M phase.


Genotype Phenotype

APC-A cdh1∆

APC-A sic1∆

APC-A sic1∆ cdc6∆2-49


Inviable in glucose (Cross, 2003).

Viable (Cross, 2003).

Viable (prediction).




Back to Predictions