Predictions (viii):
The inviability of the double mutant cdc20∆ pds1∆ can be rescued by an extra copy of genomic CDC15 or TAB6-1. Both cause more Cdc14 released from the nucleolus, thus enabling the cells to exit from mitosis even in the presence of Clb5.
| Genotype | Phenotype |
cdc20∆ pds1∆ cdc20∆ pds1∆ TAB6-1 cdc20∆ pds1∆ 2X CDC15 |
Arrests in telophase (Shirayama et al., 1999). Viable (prediction). Viable (prediction). |
cdc20∆ pds1∆ rescued by TAB6-1 or 2X CDC15.
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