Download "apc-del model"
This model simulates mutants reported by Thornton & Toczyski, 2003 that lack the essential function of APC but rescued by simultaneous deletion of PDS1 and CLB5 genes and insertion of multicopies of the genomic SIC1 gene.
Thornton, B.R., Chen, K.C., Cross, F.R., Tyson, J.J. and Toczyski, D.P. (2004). Cycling without the cyclosome: modeling a yeast strain lacking the APC. Cell Cycle 3:629-633.
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